"Lithium"was released in December 2006 as the album's second single through the band's record label Wind-up Records. An alternative version appears on the band's fourth studio album, Synthesis (2017). "Lithium" was written by the band's lead singer Amy Lee and produced by music producer Dave Fortman. Initially written on the guitar when Lee was 16 years old, the song was rearranged with a complete band performance and a piano introduction. The song is a midtempo power ballad which lyrically discusses the uncertainty of the protagonist in choosing between feelings of sorrow and happiness.
Amy Lee has been quoted saying the song is about losing the comfort of sorrow. Lithium is a mood stabilizer that would take away the sorrow that the writer holds inside and she is not ready to let go of it. She has lived with sorrow so long that losing it now would be like losing a part of herself. That is what the whole refrain is about: "Lithium, Don't want to lock myself up inside, Lithium, Don't want to forget what it feels without, Lithium, I want to stay in love with my sorrow." Lee's lyrics are often metaphorical and the words consist of double meanings. It's about her inner feelings toward herself.
Lyrics
Lithium, don't want to lock me up inside.
Lithium, don't want to forget how it feels without...
Lithium, I want to stay in love with my sorrow.
Oh, but God, I want to let it go.
Come to bed, don't make me sleep alone.
Couldn't hide the emptiness, you let it show.
Never wanted it to be so cold.
Just didn't drink enough to say you love me.
I can't hold on to me,
Wonder what's wrong with me.
Lithium, don't want to lock me up inside.
Lithium, don't want to forget how it feels without...
Lithium, I want to stay in love with my sorrow.
Don't want to let it lay me down this time.
Drown my will to fly.
Here in the darkness I know myself.
Can't break free until I let it go.
Let me go.
Darling, I forgive you... After all,
Anything is better than to be alone.
And in the end I guess I had to fall.
Always find my place among the ashes.
I can't hold on to me,
Wonder what's wrong with me.
Lithium, don't want to lock me up inside.
Lithium, don't want to forget how it feels without...
Lithium, ...stay in love with you.
I'm gonna let it go.
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